Protein aggregation is a common biological phenomenon associated with several physiological and pathological conditions. Overall, protein aggregation indicates the cellular inability to maintain its ...

Protein aggregates accumulate during aging and are linked to neurodegenerative diseases like Alzheimer's, Parkinson's or Huntington's disease. A new study by the Nyström lab at Gothenburg University, ...

A new study from Aarhus University shows that our cells' ability to clean out old protein clumps, known as aggregates, also includes a—up till now unknown—partnership with an engine that breaks down ...

In cells, many vital processes take place in membraneless molecular aggregates, which help ensure that the molecules involved are present at the right concentration and in proximity to each other.

Protein aggregation is a continuous cellular process and may be a result of misfolding caused by various stressors. Chaperone complexes, in conjunction with interacting ubiquitin E3 ligases, channel ...

When it comes to spreading from cell to cell, viruses are the masters. To disseminate their progeny, many viruses encode glycoproteins that fuse virions to plasma membranes. According to a paper in ...