In Brazilian patients with a variety of known ARDs (N=138; 87 with systemic lupus erythematosus, 45 with systemic sclerosis, 11 with Sjögren syndrome, and 10 with inflammatory myopathy) and healthy ...

† Anti-IgG as secondary antibody. ‡ Anti-IgG1, IgG2 and IgG3 as secondary antibody. IB: Immunoblotting; IIF: Immunofluorescence; LBR: Lamin B receptor; NE: Nuclear envelope; NPC: Nuclear pore complex.

Autoimmune rheumatic diseases (ARDs) represent a diverse group of conditions in which the immune system mistakenly targets the body’s own tissues, often affecting the musculoskeletal system and ...

The presence of antinuclear antibodies (ANA) indicates the possibility of autoimmunity and the indirect immunofluorescence (IIF) assay on HEp-2 cells is the standard blood test (ANA-HEp-2) used to ...

Washington, DC -- New research from Georgetown University Medical Center (GUMC) suggests that up to 40 percent of scleroderma patients will not be correctly diagnosed with the disorder using a new ...

Antinuclear antibodies (ANA) are autoantibodies directed against the nuclei of some of one’s own body cells. They are present in the blood in persons with certain autoimmune disorders. An autoimmune ...