Following her admission to intensive care unit, the patient’s daptomycin treatment was discontinued due to concern for potential daptomycin-induced hepatotoxicity. Liver function tests (LFTs) showed ...

Please provide your email address to receive an email when new articles are posted on . Daptomycin had similar efficacy to vancomycin among patients with impaired renal function receiving treatment ...

Concerns were raised about the efficacy of daptomycin for MRSA bloodstream infections in patients with impaired renal function (CrCl <50mL/min) after a recent FDA package insert change with additional ...

Background. Concerns regarding the efficacy of daptomycin for methicillin-resistant Staphylococcus aureus (MRSA) bloodstream infections in patients with impaired renal function are reflected in a ...

Background Vancomycin-resistant enterococci are a leading cause of hospital-acquired urinary tract infection and a growing concern for the clinician. The aim of this study was to evaluate the ...

Lipopeptide and β-lactam antibiotics share a common nonribosomal peptide synthetase (NRPS) mechanism for peptide assembly. 1 My first work on antibiotic biosynthesis at Eli Lilly and Company involved ...