No reaction is more elegant, more heartwarmingly satisfying than the Diels-Alder reaction. No reaction is also more nuanced. It appears deceptively simple and yet has the ability to create immense ...

In a discovery that might come as a shock—or, at the very least, an electric shock—chemists have found that a properly oriented external electric field can nudge two reagents to hook up with one ...

Researchers designed an enzyme to carry out the Diels-Alder reaction, an activity not found in nature. Enzymes have been honed over millions of years of evolution to have unique specificities for ...

First reported in 1928 by Otto Diels and Kurt Alder, the Diels-Alder reaction is one of the most relevant transformations in organic chemistry. Its capacity to generate six-membered rings enables the ...