A polygenic risk score (PRS) based on genes associated with endothelial cell function identifies patients at a higher risk of coronary artery disease, according to a new study. The risk score, which ...
A study of 130 children between the ages of 6 and 11 conducted by researchers at the Federal University of São Paulo (UNIFESP) in Brazil has identified that obesity alone can cause immediate damage to ...
In addition, Krüppel-like factor 2 (KLF2), a mechanosensitive transcription factor that regulates endothelial cell functions, was found to be upregulated. Taken together, their findings highlight the ...
The endothelial glycocalyx integrates mechanical signals with vascular biology, playing a vital role in health and disease, particularly in sepsis and diabetes.
Coronary artery disease (CAD), or the narrowing of the coronary arteries, is the leading cause of morbidity and mortality throughout the world. Atherosclerosis, or the buildup of plaque in the ...
BACKGROUND: Oscillatory shear stress (OSS), resulting from disturbed blood flow, is implicated in atherosclerotic plaque formation by incompletely understood mechanisms. This study aims to elucidate ...
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