Thanks to a recent study by researchers at IOCB Prague, it is now possible to monitor processes in living cells more ...

Fluorescent probes have emerged as a pivotal tool in the detection and imaging of hypochlorous acid (HOCl) in biological systems. HOCl, a potent reactive oxygen species generated predominantly by ...

The field of fluorescent probes tailored for nitroreductase (NTR) detection and imaging has experienced significant advancements. These probes leverage the unique catalytic property of NTR, which ...

DNA, the genetic material compacted in chromosomes, stores information to regulate all the cell processes in the body. Two decades ago, in addition to the widely known Watson-Crick double helix model ...

Photoactivable fluorescent probe, also known as photocage, is an important class of optical probes used in biological imaging. These probes typically exhibit a unique feature: the fluorescence of the ...

Cells live and die by the presence of oxygen, and low-oxygen states often indicate disease. Bacterial biofilms and the cells in solid tumors, for example, are hypoxic—that is, have abnormally low ...

Subtle cognitive decline in early Alzheimer’s disease is often indistinguishable from normal aging; as a result, the disease readily goes undiagnosed for two to three years after symptom onset. By ...

After more than a decade of developing fluorescent probes, a research team has now released the culmination of their years of work: A comprehensive collection of rhodamine-based dyes, the novel ...

Diagnosing liver cancer may have just gotten more straightforward, thanks to a new probe that makes the affected tissue glow yellow. The fluorescent labeling compound—dubbed "Sialyl Lewis Yellow"—was ...

pt. I. Design of energy transfer probes. Selection of fluorophore and quencher pairs for fluorescent nucleic acid hybridization probes / Salvatore A.E. Marras -- Choosing reporter-quencher pairs for ...

Nanjing Nuoyuan Medical Devices Co. Ltd. has discovered drug conjugates comprising a fluorescent moiety targeting hepatocyte growth factor receptors (HGFR; MET) covalently linked to crizotinib through ...

Article reviewed by Govind Kaigala, PhD at the University of British Columbia. Stay up to date on the latest science with Brush Up Summaries. In situ hybridization (ISH) is a molecular technique that ...