Some sequences in the genome cause genes to be switched on or off. Until now, each of these gene switches, or so-called enhancers, was thought to have its own place on the DNA. Different enhancers are ...

Type-2 helper T (Th2) cells play intricate roles in the inflammatory response underlying asthma. Elevated levels of the protein GATA3 stimulate the maturation of these cells. Consequently, gene ...

Organisms are made up of cells, and in each of those cells, a genome encodes the instructions for that organism to grow and survive. The human genome has at least 20,000 genes, and the expression of ...

Asthma patients experience respiratory distress due to allergens like house dust mites or pollen. However, the various triggers for asthma share a common pathway involving the release of proteins ...

Researchers have revealed a new mechanism underlying how spatial distance between specific regions of DNA is linked to bursts of gene activity. Using advanced cell imaging techniques and computer ...

Enhancers, which are thought to turn genes on by coming into physical contact with gene promoter regions through transiently forming a complex, were discovered about 45 years ago. More recently, in ...

Scientists mapped hidden DNA switches in brain support cells to understand how gene control may influence Alzheimer’s disease ...

Scientists at the Massachusetts Institute of Technology (MIT) have invented a new single-cell nascent RNA sequencing technique that lets them observe the timing of gene and enhancer activation in ...

The human genome contains about 23,000 genes, but only a fraction of those genes are turned on inside a cell at any given time. The complex network of regulatory elements that controls gene expression ...