Up to 5% of Americans may carry genetic variants associated with cancer risk, according to a cross-sectional analysis.The ...

Rare inherited genetic variants significantly increase familial lung cancer risk, offering new targets for early detection.

A study recently published in Nature Genetics identifies four genes associated with increased cancer risk and four genes with rare variants associated with reduced cancer risk. A fraction of cancers ...

Scientists at St. Jude Children's Research Hospital have revealed previously unappreciated roles for the retrotransposon LINE ...

Germline pathogenic variants contribute to 15%-20% of ovarian cancer cases, with BRCA1/2 mutations accounting for 65%-85% of these cases. Disparities in genetic testing uptake exist across racial, ...

Scientists at St. Jude Children's Research Hospital have revealed previously unappreciated roles for the retrotransposon LINE-1 in shaping the cancer genome structure and regulation.

In 2023, Jill Martin took a test that changed her life. She underwent genetic testing for breast cancer and learned she had a BRCA2 mutation, which increases one’s risk of developing breast and other ...

South African scientists have identified two new breast cancer genes -- RAB27A and USP22 -- in Black women, marking the first GWAS of its kind on the continent. This breakthrough highlights the need ...

A recent study shows that bacteria living inside colorectal tumors form distinct ecosystems that are closely linked to how ...