GEN

In vivo and In vitro Techniques Help to Unclog the Drug Discovery Process

The human genome has generated hundreds of potential new drug targets. Validation of these targets with respect to their relevance to human disease has never been more important and is a vital step in ...
Cure Today

In Vivo CAR T-Cell Approach May Lower Kidney Cancer Treatment Cost

Enabling patients to generate CAR T-cells internally could cut kidney cancer therapy costs, explained Dr. Wayne Marasco of Dana-Farber Cancer Institute. In vivo CAR T-cell therapy could drastically ...
Morningstar

Grit Biotherapeutics Invited to Deliver Oral Presentation at ASH 2025 on Breakthrough In Vivo CAR-T Therapy GT801

BEIJING, Nov. 4, 2025 /PRNewswire/ -- Grit Biotherapeutics Co., Ltd. ("Grit Bio"), a leading clinical-stage biopharmaceutical company pioneering next-generation immunotherapies, today announced that ...
GEN

Using In Vitro–In Vivo Extrapolation to Predict Human Clearance

In Vitro–In Vivo Extrapolation (IVIVE) is a method that allows researchers to predict the rate at which substances are metabolized within the human liver and are then eliminated from the body. IVIVE ...
The American Journal of Managed Care

In Vivo CAR T Takes Center Stage, With Results Shared for 4 MRD-Negative Patients

In vivo CAR T-cell therapy could revolutionize cancer treatment by bypassing traditional manufacturing, reducing costs, and minimizing adverse events. Kelonia Therapeutics' KLN-1010 has shown ...
The American Journal of Managed Care

How In Vivo CAR T-Cell Therapies Could Rewrite the Cancer Care Playbook

In vivo CAR T-cell therapies could improve access by eliminating complex logistics and reducing costs, making them more accessible to underserved populations. Traditional CAR T-cell therapies face ...