Non-alcoholic fatty liver disease (NAFLD), characterized by excessive hepatic lipid accumulation, poses a high prevalence and can progress to cirrhosis and liver cancer. To enhance preventive and ...
The intestinal epithelium forms a dynamic barrier that not only mediates nutrient absorption but also provides a critical line of defence against microbial pathogens. Its homeostasis is maintained ...
While in vivo animal models are commonly employed for pharmacokinetic studies, they are often expensive, low in throughpu,t and typically fail to accurately replicate key characteristics of the human ...
Intestine epithelium-derived exosomes serve as novel mediator in regulating hepatic lipid metabolism
Non-alcoholic fatty liver disease (NAFLD), characterized by excessive hepatic lipid accumulation, poses a high prevalence and can progress to cirrhosis and liver cancer. To enhance preventive and ...
A recent study led by Associate Professor Takuya Yamamoto and Researcher May Nakajima-Koyama has revealed that maintaining a delicate balance between interferon-gamma (IFN-γ) and extracellular ...
On the left, large intestine tissue from a healthy person; on the right, from a patient with active C. difficile infection. The white areas show the cells that line the intestine (epithelial cells).
Under healthy conditions, the intestinal epithelium fully renews itself every three to five days. Aging and exposure to ...
In vivo, the intestinal epithelium interacts with the neighboring environment through complex crosstalk, which involves components such as the immune system, tissue microenvironment, and gut microbes.
The inner lining of the small intestine nearly doubles in size during pregnancy and breastfeeding, according to new research in mice and human tissue. When you purchase through links on our site, we ...
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