The liver has a unique structure, especially at the level of individual cells. Hepatocytes, the main liver cells, release bile into tiny channels called bile canaliculi, which drain into the bile duct ...

A new type of tissue model that more accurately mimics the architecture of the liver could help develop drugs to treat MASLD.

Using human induced pluripotent stem cells, researchers have built a miniature 3D liver model that replicates the critical interaction between hepatocytes and stellate cells. As chronic liver disease ...

Human periportal assembloid, showcasing the three key cell types of the liver: portal fibroblasts (magenta), cholangiocytes (green), and hepatocyte nuclei (blue). All cell borders are delineated in ...