A new kind of microscope is giving scientists a way to watch life inside cells with a clarity that feels almost unfair.

Using machine learning to guide microscopes could reveal greater insights into the brain's connectome and deepen our ...

Both for research and medical purposes, researchers have spent decades pushing the limits of microscopy to produce ever deeper and sharper images of brain activity, not only in the cortex but also in ...

For decades, scientists have pushed the limits of microscopy to capture sharper and deeper views of the brain. Traditional light-based systems can map the cortex in detail but struggle to reach deeper ...

The accumulation of misfolded proteins in the brain is central to the progression of neurodegenerative diseases like Huntington's, Alzheimer's and Parkinson's. But to the human eye, proteins that are ...

“This is a paradigm shift,” says Donn Van Deren, PhD, postdoctoral research fellow at the University of Pennsylvania, who ...

The polarized diSPIM microscope, which can image full 3D orientation and position of molecules in cells. The instrument was constructed in the Hari Shroff lab at the National Institute of Biomedical ...

Figure 1. Conceptual illustration of label-free, multiphoton photoacoustic microscope (LF-MP-PAM). Near-infrared femtosecond laser enable us to observe endogenous NAD(P)H of neurons in brain slice and ...

Anxiety disorders are some of the most common mental health conditions in America, affecting about one in five people nationwide. But much remains unknown about the roots of anxiety in the brain. Now, ...