The muscle transmembrane protein Vangl2 helps organize the development and maintenance of connections between muscles and motor neurons, a study concludes. A skeletal muscle isn’t much use without a ...

The brain contains billions of nerve cells (i.e., neurons) which receive and integrate signals from the environment and govern the body's responses. This is made possible by synapses - contacts ...

A research group from the Sackler Faculty of Medicine and the Sagol School of Neuroscience at Tel Aviv University uncovered, for the first time, the biological mechanism causing nerve destruction in ...

A research group conducted experiments using aged mice to demonstrate that muscle denervation at the neuromuscular junction (NMJ, *1) could be appreciably offset by an NMJ formation-enhancing ...

The neuromuscular junction - where nerves and muscle fibers meet - is an essential synapse for muscle contraction and movement. Improper function of these junctions can lead to the development of ...

Conducting a review of data published over a 25-year period, researchers highlight the importance of this type of research they say offers insight that drives the success of SMA treatment. A group of ...

Scanning electron microscopy image of a human neuromuscular junction generated in microfluidic devices. Human induced pluripotent stem cell-derived motor neuron axons fan out and embed themselves into ...

The nervous system makes use of a diverse set of mechanisms to maintain synaptic function in the face of challenges that might alter neuronal excitability, yet these homeostatic processes are not well ...

The brain contains billions of nerve cells (i.e., neurons) which receive and integrate signals from the environment and govern the body's responses. This is made possible by synapses - contacts ...