The hormone estrogen—which female animals typically have more of than males—triggers a molecular cascade in the gut that ...
Osteoarthritis can be a debilitating disease, rendering regular movements painful. Researchers have now identified a signaling pathway that transmits this pain, with a study in mice finding that ...
Recent studies are pointing to the fact that kindness can decrease pain and lessen stress. As Dr. Kapoor notes, pain is largely an evolutionary mechanism to enhance survival and, hence, is largely ...
New research reveals previously unknown ways opioid receptors can function, opening the door to safer pain treatments.
Stanford Medicine investigators have replicated, in a lab dish, one of the most prominent human nervous pathways for sensing pain. This nerve circuit transmits sensations from the body’s skin to the ...
Researchers integrated four organoids that represent the four components of the human sensory pathway, along which pain signals are conveyed to the brain. Stimulation of the sensory organoid (top) by ...
Scientists created a model of the human pain pathway in a dish by connecting four separate brain organoids. The feat should help them understand sensory disorders like those affecting pain perception.
RALEIGH – Researchers from North Carolina State University have discovered that a particular molecular signaling pathway plays an important role in producing osteoarthritis (OA) pain. Using a mouse ...
SereNeuro Therapeutics revealed promising results for SN101, a first-in-class iPSC-derived therapy designed to treat chronic osteoarthritis pain while protecting joint tissue. Instead of blocking pain ...
Researchers have discovered that a particular molecular signaling pathway plays an important role in producing osteoarthritis (OA) pain. Using a mouse model of painful osteoarthritis, they show that ...
Scientists have re-created a pain pathway in the brain by growing four key clusters of human nerve cells in a dish. This laboratory model could be used to help explain certain pain syndromes, and ...