Aided by two molecular control factors, the spliceosome rejects pre-mRNA that could be incorrectly spliced. While GPATCH1 detects the defective pre-mRNA, DHX35 removes it from the spliceosome, which ...
Researchers at the University of Toronto have shown that an important class of DNA-binding factors can also bind to RNA, regulating gene expression through various mechanisms. The study significantly ...
A new study has discovered an unprecedented pathway producing telomerase RNA from a protein-coding messenger RNA (mRNA). For the very first time, a study led by Julian Chen and his group in Arizona ...
Two molecular control factors play a decisive role in what is known as splicing, the cutting and assembly of mature messenger RNA—a prerequisite for protein synthesis in the cell. The poorly ...