The sarcoplasmic reticulum (SR) is a specialised organelle in skeletal muscle fibres that plays a pivotal role in regulating calcium dynamics crucial for muscle contraction and relaxation. Acting as ...

The mechanism of skeletal muscle contraction is a process that relies on calcium signaling. However, the physiological role of calcium-induced calcium release (CICR) through the ryanodine receptor ...

In a serendipitous discovery, UC San Diego researchers using cryo-EM technology captured the first visualizations of the 3-D structure of the muscle acetylcholine receptor in fetal and adult muscles.

Researchers engineered mice with a mutation (E3896A) in the RyR1 calcium-binding site, eliminating calcium-induced calcium release (CICR) without affecting depolarization-induced calcium release. The ...

Scientists have developed a specially formulated bioink, which contains microparticles engineered for sustained delivery of insulin-like growth factor-1 (IGF-1). This delivery enhances the formation ...

Researchers have just made the unexpected discovery of a novel organization of muscle fibers in Parophidion vassali, a fish that lives in the Mediterranean Sea and, like many fish, uses specialized ...