The pneumococcus undergoes spontaneous phase variation between an opaque and a transparent colony form. In an animal model of systemic infection following intraperitoneal inoculation of mice, the ...

The ability of pneumococcal conjugate vaccine (PCV) to decrease transmission by blocking the acquisition of colonization has been attributed to herd immunity. We describe the role of mucosal ...

Vaccines that protect people from infection by Streptococcus pneumoniae, which kills up to one million children ever year worldwide, train the immune system to recognize the pathogen’s thick sugar ...

Washington, DC - May 19, 2020 -- Vaccines that protect people from infection by Streptococcus pneumoniae, which kills up to 1 million children ever year worldwide, train the immune system to recognize ...

Streptococcus pneumonia is an encapsulated bacteria with a polysaccharide capsule an essential factor in virulence. About 90 distinct pneumococcal serotypes have been identified throughout the world, ...