The University of Alabama at Birmingham

Why some organ transplants trigger harmful antibody responses

UAB researchers discover that the immune system consistently targets the same region of mismatched HLA proteins after organ ...
Medscape

Trends in HLA Antibody Screening and Identification and Their Role in Transplantation

Determining the specificity of HLA antibodies is arguably one of the most important contributions by the HLA laboratory today. For patients that have low-to-moderate levels of antibody, using a ...
News Medical

Common genetic variation responsible for mediating SARS-CoV-2 asymptomatic infection

Have you ever wondered why some people never became sick from COVID-19? A study published today in Nature shows that common genetic variation among people is responsible for mediating SARS-CoV-2 ...
Open Access Government

Join HT in funding a breakthrough in clinical genomics

Haploid Technologies has developed a groundbreaking new technology that enables precise assignment of phase across multiple ...
ascopubs.org

Assessment of Functional Status of Human Leukocyte Antigen Class I Genes in Cancer Tissues in the Context of Personalized Neoantigen Peptide Vaccine Immunotherapy

Somatic mutations in HLA genes were detected in the tumor data of five patients, and somatic HLA gene loss of heterozygosity was identified in the tumor data of five patients. Complete or partial ...