The tide of the blood coagulation cascade turns by a switch in thrombin specificity. Two new structures reveal how thrombomodulin's EGF domains flip the switch by blocking old substrates and docking ...

Researchers at Kumamoto University have developed a highly sensitive blood test that can detect subtle differences in how ...

The glycoprotein V of the blood platelets is an important switch point for haemostasis and thrombus formation. This new finding could have great clinical potential. When our blood vessels are injured ...

STOCKHOLM, Sweden – An experimental agent that prevents the formation of blood clots earlier in the coagulation process than other agents has cleared its first hurdle in becoming a potential new ...

Fibrin plays a major role in stopping bleeding and healing wounds. However, if fibrin is formed in excess, e.g., in chronic wounds, thrombosis and subsequent vascular occlusions can occur. Therefore, ...

Researchers at the Indian Institute of Science (IISc) have developed an artificial metal-based nanozyme that can potentially be used to clamp down on abnormal blood clotting caused by conditions like ...