First-ever biologically authentic computer model was completed of the HIV-1 virus liposome. Key finding from the simulations is the formation of sphingomyelin and cholesterol rich microdomains. HIV-1 ...
Scientists at the Electron Bio-Imaging Centre (eBIC) at Diamond Light Source, in the U.K., have harnessed a new technique, using cryo-electron tomography (cryoET) and subtomogram averaging (STA) to ...
A computational model of the more than 26 million atoms in a DNA-packed viral capsid expands our understanding of virus structure and DNA dynamics, insights that could provide new research avenues and ...
A new combination of microscopy methods has revealed exquisite detail of the virus assembly process used by herpes simplex virus during replication. The research, published today as a Reviewed ...
Gene Therapy Analytics and Manufacturing, a recent conference organized by the Cambridge Healthtech Institute and held in San Diego, described itself as a way to take “an in-depth look at the ...
Because viruses have to hijack someone else’s cell to replicate, they’ve gotten very good at it—inventing all sorts of tricks. A new study from two University of Chicago scientists has revealed how ...
Gilead Sciences announced a significant milestone: the U.S. FDA accepted their New Drug Applications (NDAs) for lenacapavir (LEN), a groundbreaking twice-yearly injectable HIV-1 capsid inhibitor for ...
When is a container not just a container? For the HIV-1 virus, a double layer of fatty molecules called lipids not only serves as its container, but also plays a key role in the virus's replication ...
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