Fred Hutch Cancer Center scientists have developed an experimental strategy to give genetically engineered CAR T cells help they'd normally find within lymph nodes — but on the go, within the tumor.

Aggregating ‘negative’ immunotherapy trials can uncover reproducible immune perturbations that are missed in single studies, reframing lack of clinical benefit as potentially informative biologic ...

Scientists have uncovered new genetic rules that determine whether the immune system’s “killer” T cells remain powerful long-term defenders or become worn out and ineffective. By building a detailed ...