Using the Very Large Telescope (VLT), astronomers have discovered a compact binary system consisting of two white dwarfs in the center of a nearby globular cluster designated NGC 6397. The finding was ...

Significant predictors of 28-day mortality in critically ill patients with systemic sclerosis include male sex and BMI.

University of Virginia School of Medicine researchers have uncovered a possible way to prevent the dangerous hardening of skin and organs in people with systemic scleroderma, a rare autoimmune disease ...

Comorbidity. Just seeing that word makes me cringe. It means having two or more coexisting, and often chronic, health conditions. For many of us in the rare disease community, comorbidity means ...

Background Systemic sclerosis, also known as scleroderma, is a complex, multi-organ disease which causes substantial and progressive fibrosis of the skin and internal organs, including the heart and ...

Scleroderma is a rare autoimmune disease involving an overproduction of the protein collagen. Linear scleroderma usually begins as a streak of hardened, waxy, discolored skin on the forehead, an arm, ...

Several factors were associated with increased pain among patients with systemic sclerosis, including the pain type, pain location, and disease subtype. Nearly all patients with systemic sclerosis ...

Systemic sclerosis (SSc) is a rare autoimmune disease that can harden the skin, impair blood flow, and damage internal organs such as the lungs and kidneys. But no two patients experience the disease ...

Patients with scleroderma renal crisis demonstrated specific enrichment of CD14+ monocytes with increased EGR1 expression and activation of NF-κB–related pathways. Trajectory analysis indicated that ...

Most VVD in clinical trials have been shown to exert anti-fibrotic effects – but findings are mixed around whether they also improve pulmonary function tests and prevent progression of SSc-associated ...