ahajournals.org

Adipocyte-Specific Deficiency of NADPH Oxidase 4 Delays the Onset of Insulin Resistance and Attenuates Adipose Tissue Inflammation in Obesity

Obesity is associated with insulin resistance and adipose tissue inflammation. Reactive oxygen species (ROS) increase in adipose tissue during the development of obesity. We previously showed that in ...
ahajournals.org

Glucose Metabolism in Cardiac Hypertrophy and Heart Failure

Heart failure is one of the leading causes of death worldwide and has been singled out as an emerging epidemic. 1, 2 With a 5‐year survival rate of 50%, heart failure poses a tremendous burden on our ...
C&EN

Substrate Specificity Combined with Stereopromiscuity in Glutathione Transferase A4-4-Dependent Metabolism of 4-Hydroxynonenal

‡ Department of Medicinal Chemistry, Box 357610, University of Washington, Seattle, Washington 98195 § Department of Biological Structure, Biomolecular Structure Center, Box 357420, University of ...
C&EN

Lipid Peroxidation Products HNE and ONE Promote and Stabilize Alpha-Synuclein Oligomers by Chemical Modifications

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