Add Yahoo as a preferred source to see more of our stories on Google. We've known about spermine for more than 150 years: its regular job has to do with the body's metabolism, the business of ...

The small molecule spermine has the potential to stop the toxic build-up of proteins in the brain that characterizes diseases like Alzheimer's and Parkinson's, researchers have found – and it works a ...

Jinghui Luo is a researcher at the Center for Life Sciences at the Paul Scherrer Institute PSI. He studies accumulations of so-called amyloid proteins, which lead to nerve damage in the brain. His ...

Spermine-modified acetalated dextran nanoparticles (AcDx-Sp NPs) show a higher loading of SPM and uniform spherical morphology with a size range of 105 nm. After impregnation of SPM, the nanovaccine ...

Sperm have a temperature-sensitive “thermostat” called CatSper that activates when temperatures exceed 33.5°C (92.3°F), explaining why testicles need to stay cooler than body temperature. Seminal ...

Conjugates between polyamines and hydroxycinnamic acids are found on the pollen surface of all higher plants, both mono- and dicots. But we don’t know why they are there. Delporte et al. (2018) have ...

Polyamines have been reported to be associated with neurological function, but the associations between polyamines and the prognosis of ischemic stroke remain unclear. We aimed to prospectively ...

Janssen Pharmaceutica NV has divulged pyrazolopyrimidines acting as spermine oxidase (polyamine oxidase 1; SMOX) inhibitors reported to be useful for the treatment of colorectal cancer.

Hand-foot syndrome (HFS) is a common capecitabine-based chemotherapy-related adverse event (CRAE) in patients with colorectal cancer (CRC). It is of great significance to comprehensively identify ...