CD27 is a member of the tumor necrosis factor receptor superfamily. [5] It is currently of interest to immunologists as a co-stimulatory immune checkpoint molecule, and is the target of an anti-cancer …

Nov 13, 2025 · CD27 (CD27 Molecule) is a Protein Coding gene. Diseases associated with CD27 include Lymphoproliferative Syndrome 2 and Combined T Cell And B Cell Immunodeficiency.

Jun 29, 2025 · The CD27 protein on T cells acts as a key indicator of immune function, helping define a cell’s memory potential and serving as a target in therapy.

Feb 8, 2025 · The CD27 (+) B-cell population was found to highly express CXCR3 in chronic hepatitis C (CHC), thus suggesting that the CD27 (+) B-cell population was recruited from peripheral blood to …

CD27 is a member of the tumor necrosis factor receptor (TNFR) superfamily, which is fundamental in mediating immune responses. Understanding its structure is vital for elucidating its roles in T and B …

Feb 28, 2023 · CD27 is a costimulatory receptor of the TNF receptor superfamily expressed on lymphocytes CD27 is triggered by its unique ligand CD70, which is expressed on immune cells and …

Mar 19, 2013 · The CD27 gene was studied because flow cytometric analysis during diagnostic work-up showed absence of CD27 on all patient lymphocytes. CD27 is recognized as a marker for memory B …

Dec 12, 2022 · Memory B cells are essential for our immunological memory and respond rapidly to reinfection. CD27 is a widely used cell surface marker for human memory B

CD27 is a costimulatory molecule associated with CD27 Deficiency, a condition characterized by immunodeficiency, EBV lymphoproliferative disease, reduced T cell proliferation, and progressive …

2 days ago · The team from the University of Southampton’s Centre for Cancer Immunology focused their efforts on an immune receptor called CD27. CD27 needs a matching key (ligand) to activate T …